
Eric Schoen
D.O.B: August 30, 1956
Employment
KU Leuven, Faculty of Bioscience Engineering / Guest Professor
2018 - present
Dutch Organization of Applied Scientific Research TNO, Zeist / Senior Statistical Consultant
1987 - 2020
University of Antwerp, Faculty of Applied Economics / Guest Professor
2006 - 2017
Eindhoven University of Technology, Dept. of Mathematics and Computer Science / Researcher
2002-2006
Erasmus University, Rotterdam, Institute of Public Health and Social Medicine / Scientific Researcher
1984-1987
Vrije Universiteit, Amsterdam, Dept. of Biology / Scientific Assistant
1983-1984
Education
Eindhoven University of Technology / PhD Applied Statistics
1994-2000
Vrije Universiteit Amsterdam / MSc Theoretical Biology
1978-1983
Vrije Universiteit, Amsterdam / BSc Biology and Chemistry
1974-1978
Refereed publications
- Schoen, E.D., Jager, J.C., van Verseveld, H.W., and Stouthamer, A.H. (1985) Statistical analysis of growth limitations in Paracoccus denitrificans: an experiment with a completely randomized two-way factorial design with replications. Antonie van Leeuwenhoek 51: 11-24.
- Arts, J.H.E., Zwart, A., Schoen, E.D., and Klokman-Houweling, J.M. (1989) Determination of concentration-time-mortality relationships vesus LC50s according to OECD guideline 403. Experimental Pathology 37: 62-66.
- Zwart, A., Arts, J.H.E., Klokman-Houweling, J.M., and Schoen, E.D. (1990) Determination of concentration-time-mortality relationships to replace LC50 values. Inhalation Toxicology 2: 105-117.
- Smeets, J.F.M., Odink, J., Visser, I.J.R., Schoen, E.D., and Snijders, J.M.A. (1990) Haematology and blood-chemistry for predicting abscesses and other abnormalities in slaughtered pigs. The Veterinary Quarterly 12: 146-151.
- Wolff, K., Schoen, E.D., and Peters – van Rijn, J. (1993) Optimizing the generation of random amplified polymorphic DNA in chrysanthemum. Theoretical and Applied Genetics 86: 1033-1037.
- Schoen, E.D. (1996) Statistical designs in combination toxicology: a matter of choice. Food and Chemical Toxicology 34: 1059-1065.
- Groten, J.P., Schoen, E.D., and Feron, V.J. (1996) Use of factorial designs in combination toxicity studies. Food and Chemical Toxicology 32: 1083-1089.
- Groten, J.P., Schoen, E.D., van Bladeren, P.J., Kuper, C.F., van Zorge, J.A., and Feron, V.J. (1997) Subacute toxicity of a combination of nine chemicals in rats: detecting interactive effects with a fractionated two-level factorial design. Fundamental and Applied Toxicology 36: 15-29.
- Schoen, E.D., and Wolff, K. (1997) Design and analysis of a fractional 4^13^12^5 split-plot experiment. Journal of Applied Statistics 24: 409-419.
- Groten, J.P., Tajima, O., Feron, V.J., and Schoen, E.D. (1998) Statistically designed experiments to screen chemical mixtures for possible interactions. Environmental Health Perspectives 106, Suppl 6: 1361-1365.
- Schoen, E.D. (1999) Designing fractional two-level experiments with nested error structures. Journal of Applied Statistics 26: 495-508.
- Maas, W.J.M., de Graaf, I.A.M., Schoen, E.D., Koster, H.J., van de Sandt, J.J.M., and Groten, J.P. (2000) Assessment of some critical factors in the freezing technique for the cryopreservation of precision-cut rat liver slices. Cryobiology 40: 250-263.
- Schoen, E.D., and Kaul, E.A.A. (2000) Three robust scale estimators to judge unreplicated experiments. Journal of Quality Technology 32: 276-283.
- Tajima, O., Schoen, E.D., Feron, V.J., and Groten, J.P. (2002) Statistically designed experiments in a tiered approach to screen mixtures of Fusarium mycotoxins for possible interactions. Food and Chemical Toxicology 40: 685-695.
- Bingham, D.R., Schoen, E.D., and Sitter, R.R. (2004) Designing fractional factorial split-plot experiments with few whole-plot factors. Journal of the Royal Statistical Society Series C 53: 325-339; Corrigendum: Journal of the Royal Statistical Society Series C 54: 955-958.
- Schoen, E.D. (2004) Dispersion-effects detection after screening for location effects in unreplicated experiments. Journal of Statistical Planning and Inference 126: 289-304.
- Feron, V.J., Groten, J.P., Hermus, R.J.J., Jonker, D., Meijerman, I., Mulder, G.J., Salmon, F., and Schoen, E.D. (2005) Designing experiments for food-drug synergy: safety aspects. In: Food-drug synergy and safety (L.V. Thompson and W.E. Ward, editors; Boca Raton: CRC/Taylor & Francis).
- Schoen, E.D. (2009) All orthogonal arrays with 18 runs. Quality and Reliability Engineering International 25: 467-480.
- Schoen, E.D., Eendebak, P.T., and Nguyen, M.V.M. (2010) Complete enumeration of pure-level and mixed-level orthogonal arrays. Journal of Combinatorial Designs 18: 123-140.
- Schoen, E.D. (2010) Optimum designs versus orthogonal arrays for main effects and two-factor interactions. Journal of Quality Technology 42: 197-208.
- Schoen, E.D., Goos, P., and Jones, B. (2011) A split-plot experiment with factor-dependent whole plot sizes. Journal of Quality Technology 43: 66-79.
- Schoen, E.D., and Mee, R.W. (2012) Two-level designs of strength 3 and up to 48 runs. Journal of the Royal Statistical Society Series C 61: 163-174.
- Sartono, B., Goos, P., and Schoen, E.D. (2012) Classification of three-level strength-3 arrays. Journal of Statistical Planning and Inference 142: 794-809.
- Schoen, E.D. (2012) Designs for two-stage intensive screening of pharmaceutical production processes. Statistics in Biopharmaceutical Research 4: 336-347.
- Schoen, E.D., and Van der Voort Maarschalk, K. (2012) Adding a factor in the course of a design space characterization. Journal of Pharmaceutical Innovation 7: 163-173.
- Schoen, E.D., Sartono, B., and Goos, P. (2013) Optimum blocking for general resolution-3 designs. Journal of Quality Technology 45: 166-187.
- Schoen, E.D., Rubingh, C.M., Wopereis, S., and Van Erk, M. (2013) Controlling false discovery rates in factorial experiments with between-subjects and within-subjects tests. BMC Research Notes 6: 204.
- Garai, M., Schoen, E., Behler, G., Bragado, B., Chudalla, M., Conter, M., Defrance, J., Demizieux, P., Glorieux, C., and Guidorzi, P. (2014) Repeatability and reproducibility of in situ measurements of sound reflection and airborne sound insulation index of noise barriers. Acta Acustica / Acustica 100: 1186-1201.
- Schoen, E.D., and Goos, P. (2015) Discussion on ‘The case against normal plots of effects’. Journal of Quality Technology 47: 114-118.
- Sartono, B., Goos, P., and Schoen, E.D. (2015) Blocking orthogonal designs with mixed integer linear programming. Technometrics 57: 428-439.
- Sartono, B., Goos, P., and Schoen, E.D. (2015) Constructing general orthogonal fractional factorial split-plot designs. Technometrics 57: 488-502.
- Jones, B., Schoen, E.D., and Montgomery, D.C. (2016) A comparison of two-level designs to estimate all main effects and two-factor interactions. Quality Engineering 28: 369-380.
- Eendebak, P.T., and Schoen, E.D. (2017) Two-level designs to estimate all main effects and two-factor interactions. Technometrics 59: 69-79.
- Mee, R.W., Schoen, E.D., and Edwards, D.J. (2017) Selecting an orthogonal or nonorthogonal two-level design for screening. Technometrics 59: 305-318.
- Kooter, I.M., Gröllers-Mulderij, M., Duistermaat, E., Kuper, F., and Schoen, E.D. (2017) Factors of concern in a human 3D cellular airway model exposed to aerosols of nanoparticles. Toxicology in Vitro 44: 339-348.
- Schoen, E.D., Vo-Thanh, N., and Goos, P. (2017) Two-level orthogonal screening designs with 24, 28, 32, and 36 runs. Journal of the American Statistical Association 112: 1354-1369.
- Vo-Thanh, N., Jans, R., Schoen, E.D. and Goos, P. (2018) Symmetry breaking in mixed integer linear programming formulations for blocking two-level orthogonal experimental designs. Computers & Operations Research 97: 96-110.
- Schoen, E.D., Eendebak, P.T., and Goos, P. (2019) A classification criterion for definitive screening designs. The Annals of Statistics 47: 1179-1202.
- Schoen, E.D., Vo-Thanh, N., and Goos, P. (2019) Orthogonal blocking arrangements for 24-run and 28-run two-level designs. Journal of Quality Technology 51: 143-158.
- Goos, P. and Schoen, E.D. (2019) Discussion Discussion on “Søren Bisgaard’s contributions to Quality Engineering: Design of experiments”. Quality Engineering, 31: 157-161.
- Vazquez, A.R., Goos, P., and Schoen, E.D. (2019) Constructing two-level designs by concatenation of strength-3 orthogonal arrays. Technometrics 61: 219-232.
- Vazquez, A.R., Goos, P., and Schoen, E.D. (2020) Projections of definitive screening designs by dropping columns: selection and evaluation. Technometrics 62: 37-47.
- Vo-Thanh, N., Schoen, E.D., and Goos, P. (2020) Row-column arrangements of regular and nonregular fractional factorial two-level designs. Journal of Quality Technology 52: 304-322.
- Vo-Thanh, N., Goos, P. and Schoen, E.D. (2020) Integer programming approaches to find row–column arrangements of two-level orthogonal
experimental designs. IISE Transactions 52: 780-796. - Schoen, E.D. and Wopereis, S. (2020) A new randomization procedure based on multiple covariates and applicable to parallel studies with simultaneous enrollment of all subjects prior to intervention. BMC Medical Research Methodology 20: 222.
- Vazquez, A.R., Schoen, E.D. and Goos, P. (2021) A mixed integer optimization approach for model selection in screening experiments. Journal of Quality Technology 53: 243-266.
- Vazquez, A.R., Schoen, E.D. and Goos, P. (2021) Two-level orthogonal screening designs with 80, 96, and 112 runs, and up to 29 factors. Journal of Quality Technology, in press.
- Kort, R., Schlösser, J., Vazquez, A.R., Atukunda, P., Muhoozi, G.K.M., Wacoo A.P., Sybesma W.F.H., Westerberg A.C., Iversen P.O., and Schoen E.D. (2021) Model Selection Reveals the Butyrate-Producing Gut Bacterium Coprococcus eutactus as Predictor for Language Development in 3-Year-Old Rural Ugandan Children. Frontiers in Microbiology 12: 1406.
Awards
American Society for Quality, Statistics Division: Lloyd Nelson Award 2011.
Invitations
- European Congress on Combination Toxicology, Velthoven, Netherlands: ‘Statistical Designs in Combination Toxicology: a Matter of Choice’ (October 11-13, 1995).
- Spring Research Conference (SRC) 2002, Ann Arbor, MI, USA: ‘Fractional Split-Plot Experiments with Replicated Settings of Whole-Plot Factors’ (May 20-22, 2002).
- DAE 2005, Sante Fe: ‘Enumeration and Selection of Small Orthogonal Strength-3 Arrays’ (October 12-14, 2005).
- Workshop of the Belgian Branch of the European Network for Business and Industrial Statistics (bENBIS), Antwerp: ‘Two-Level Fractional Factorial Split-Plot Designs’ (June 2, 2006).
- 2006 International Conference on Design of Experiments and Its Applications, Tianjin, China: ‘Orthogonal Arrays of Strength 3 with Full Estimation Capacities’ (July 9-13, 2006).
- DEMA 2008, Cambridge, UK: ‘A blocking strategy for orthogonal arrays of strength 2’ (August 11-15, 2008)
- Workshop on Quality Improvement Methods, University of Dortmund, Germany: ‘Very fast enumeration of orthogonal arrays’ (May 22-23, 2009).
- ENBIS 2010, University of Antwerp, Belgium: ‘Optimum designs versus orthogonal arrays’ (September 13-15, 2010).
- ICODOE 2011, University of Memphis, Memphis TN, USA: ‘Better alternatives than generalized aberration to select strength-three multi-level designs’(May 11-13, 2011).
- DEMA 2011, Cambridge, UK: ‘Split-plot experiments with factor-dependent whole plot sizes’ (August 30-September 2, 2011).
- Fall Technical Conference 2011, Kansas City MO, USA: ‘Mixed-level designs for main effects and two-factor interactions: generated from scratch or catalog based?’ (October 13-14, 2011).
- JSM 2013, Montreal Québec, Canada: ‘Constructing general orthogonal fractional factorial split-plot designs’ (August 3-8, 2013).
- Spring Research Conference 2016, Chicago IL, USA: ‘Two-Level Designs to Estimate All Main Effects and Two-Factor Interactions’ (May 25-27, 2016)
- Conference on Experimental Design and Analysis 2018, Hsinchu, ROC: ‘A connection between orthogonal two-level designs and Definitive Screening Designs’ (December 13-15, 2018)
- 8th International Conference on Risk Analysis and Design of Experiments, Vienna, Austria: ‘A connection between orthogonal two-level designs and Definitive Screening Designs’ (April 23-26, 2019)
PhD students
- Man Nguyen: Computer algebraic methods for the construction of designs of experiments. PhD thesis Eindhoven University of Technology, October 2005 (co-advisor).
- Bagus Sartono: Orthogonal experimental designs under complete and restricted randomization. PhD thesis University of Antwerp, May 2012 (advisor).
- Nha Vo-Thanh: Two-level orthogonal experimental designs in the presence of zero, one or two blocking factors. PhD thesis University of Antwerp, September 2016 (advisor).
- Alan Vazquez, University of Antwerp: Orthogonal experimental designs for screening: construction and analysis. PhD thesis University of Antwerp, May 2018 (advisor).
MSc students
- Enrico Kaul
- Peter van den Berg
- Volkert Siersma
- Ruben Snepvangers
- Vincent Brouérius van Nidek